S9 and Activation of Pro-Mutagens

Product No. 5031S9 S9 Activation Enzymes (SOS-ChromoTest Kit).

S9 is a crude liver enzyme extract that can, under certain conditions, convert materials without any genotoxic activity to active genotoxic entities. The chemical process involved may be different for different materials. In addition, the lifetime of the activated moieties is extremely variable: some may be extremely short-lived. This is the reason for incubating the S-9 with the bacteria and the tested material at the same time during the assays.

S9 Activation Enzymes include:

Buffers, NADP, Sugars, Liver Enzymes and Controls

It is recommended that the SOS-ChromoTest kit be tested with and without the S9 Activation Enzymes.  EBPI's S9 Activation Enzymes contain enough reagents to be used in parallel with the SOS-ChromoTest kit.  The 5031S9 Activation Enzymes contain enough liver enzymes and reagents for 3 SOS-ChromoTests (please contact EBPI This email address is being protected from spambots. You need JavaScript enabled to view it. ) for modification of the 5031S9 to meet your requirements).