EBPI is welcoming a new line of toxicity tests to our growing line of bioassays.  Our BioTox line of Vibrio Fischeri bioluminescent bacterial inhibition tests were developed for ISO standardization for your laboratory requirements.  These Vibrio Fischeri tests include the following:

Product No. 1243-1000 

Product No. 1243-500  

The WaterTox EVO (Evolution) Vibrio Fischeri kit is packaged as a cost effective alternative to the 1232-1000 Water Toxicity Kit.  Bacterial reagents are packaged to permit less reagent waste for smaller sample numbers.  The Vibrio Fischeri operation protocol has been simplified to reduce pipetting steps and a NaN3 tablet is included instead of a OAS solution.  Results can be interpreted by any approved ISO luminometer.

Product No. 1243-700 The LumoPlate Vibrio Fischeri test allows complete solutions for clients requiring a more accurate and robust assay system.   The LumoPlate Vibrio Fischeri assay accounts for sample coloration and turbidity and can be used for direct measurement of soil and sediment samples without time consuming correction procedures.  The Vibrio Fischeri bacteria and reagents are packaged to accommodate 96 endpoints per run (10 test per kit). 

 Product No. 1243-70 

 LumoStix Vibrio Fischeri test includes reagents, diluent and the "LumoStix".  This Vibrio Fischeri contact test allows for 20 individual measurements (Vibrio Fischeri bacteria are packaged to allow for 4 determination per vial - the LumoStix is designed to be used with the Kikkoman PD30 luminometer).

Whats new for 2017?

CONTACT SEDIMENT TOXICITY AND GENOTOXICITY TESTS:

EBPI has developed and launched the contact sediment test for both detection of toxicity and genotoxicity.

The SediTox platform is based on the novel bacterial strains also used in the EBPI line of Toxi-ChromoTest, SOS-ChromoTest and the UMUChormoTest products as well as Vibrio fischeri bioluminescent bacteria.

The SediTox Kit employs a direct sediment exposure method to assess total responses from all soluble, insoluble, organic, inorganic, and volatile molecules in a given sample.

BENEFITS OF THE SEDITOX

• Rapid bacterial-based colorimetric (or bioluminescent) bioassay for acute toxicity or genotoxicity . 
• The  assay will detect additive, synergistic and antagonistic effects in toxicant mixtures. 
• Sensitive to a wide spectrum of toxic (genotoxic) substances. 
• The EBPI Express SOS and UMU Strains can be utilized to detect genotoxic potential of metabilites. 
• Detection of direct toxicity (genotoxicity) without the need for labour intensive extraction procedures.

Whats new for 2016?

Ames-Express Bacterial Strains:

EBPI is proud to officially announce the release of our NEW Ames bacterial strains, called the Ames-Express^TM strains.  Ames-Express^TM strains are constructed from normal Ames bacterial strains (TA100, TA98, TA1535, TA97a, TA1538), but have been engineered to also express either human P450 or GST-theta liver enzymes internally, which promotes bioactivation of xenobiotic molecules into DNA reactive species in the absence of an S9 mix.  

A few of the benefits of the Ames-Express strains include:

• Short-lived, reactive metabolites are created within the bacterial cell in close proximity to target DNA.
  
• Eliminates the need to incorporate S9 liver extract.
• Improvements in sensitivity and selectivity compared to traditional Ames assays.
• Response suppression from interactions with S9 lysate mix is eliminated.
• The system expresses recombinant human proteins rather than rat liver extract, which improves extrapolation of mutagenicity data to human health endpoints.

Please visit, EBPI Toxicity Test/Ames Express for further information or download our Ames Express Handout here.